When a player is moving quickly, such as when falling or in a vehicle that can be driven, the menu on one's hand can't be clicked on even when the cursor beam is clearly aimed at it. It's as if the menu is being rendered on your hand but the actual interact surface is being left behind.

This can result in some problematic situations such as being caught in an infinite falling loop and respawning only to fall again without being able to escape into another world, or being unable to unmute the microphone if in a vehicle being driven by someone else.